ZP282 - Organic chemistry II

Course specification
Course title		Organic chemistry II
Acronym		ZP282
Study programme		Biochemical Engineering and Biotechnology,Chemical Engineering
Module
Lecturer (for classes)		prof. dr Dušan Mijin prof. dr Nataša Valentić
Lecturer/Associate (for practice)		prof. dr Saša Drmanić prof. dr Aleksandar Marinković prof. dr Jasmina Nikolić prof. dr Nemanja Trišović doc. dr Nevena Prlainović
Lecturer/Associate (for OTC)
ESPB		7.0	Status
Condition		Organic chemistry I	Облик условљености
The goal		Introduction to the basic concepts of the structure and reactions of organic compounds, the nomenclature of organic compounds, dependence of the physical and chemical properties and molecular structure, the possibilities of synthesis of organic molecules and their application. Correlation between the structure and reactivity of organic molecules and its application.
The outcome		Students will acquire basic theoretical knowledge of organic chemistry and together with the gained laboratory skills it will allow them to solve problems of the synthesis and reactivity of organic molecules.
Contents
Contents of lectures		Amines and their derivatives: synthesis and properties. Correlation between the structure and basicity of amines. Diazotization and diazo coupling reactions. Application in the synthesis. Nitro compounds: structure and properties. Aromatic nitro compounds, explosives. Aldehydes and ketones: structure, properties and synthesis. Nucleophilic addition to carbonyl group. Enolates and enols. Keto-enol equilibrium. Aldol reaction. Properties of α, β-unsaturated aldehydes and ketones and the conjugate addition reactions. Carboxylic acids: structure, properties and synthesis. Correlation between the structure and acidity. Reactions of carboxylic acids. Conversion to derivatives. Nucleophilic acyl substitution. α-Halogen substituted acids and their reactions. Carboxylic acids derivatives: acyl-halides, anhydrides, esters, amides and nitriles. The structure, properties, synthesis and reactivity in nucleophilic acyl substitution reaction. Synthesis and reactions of β-dikarbonilnih compounds. Ester enolates and Claisen condensation. Malonic ester and acetoacetic ester synthesis. Strategy of synthesis. Carbohydrates: polyfunctional natural compounds. Lipids. Heterocyclic aromatic compounds: structure and properties. Five- and six-member rings. Synthesis and characteristic reactions. Condensed ring systems. Amino acids, proteins and nucleic acids.
Contents of exercises		Synthesis of 6 organic compounds that illustrate the most important organic reactions.
Literature
K.P.C. Volhard, N.E. Šor, Organska hemija: struktura i funkcija, 4. izdanje, Data Status: Nauka, Beograd: Planeta print, 2004. (Original title) N.E. Šor, Uputstvo za rešavanje zadataka sa rešenjima. Organska hemija: struktura i funkcija, 4. izdanje, Data Status: Nauka, Beograd: SP Print, 2006. (Original title) Grupa autora, Eksperimentalna organska hemija, 4. izdanje, TMF, Beograd, 2011. (Original title) Grupa autora, Zbirka zadataka iz organske hemije, TMF, Beograd, 2000. (Original title) T.W. Graham Solomons, C.B. Fryhle, Organic Chemistry, 9th ed., John Wiley Inc, New York, 2007. (Original title)
Number of hours per week during the semester/trimester/year
Lectures	Exercises	OTC	Study and Research	Other classes
4	0	2
Methods of teaching		Lectures, Organic Chemistry Laboratory, Written mid-term exams.
Knowledge score (maximum points 100)
Pre obligations		Points	Final exam	Points
Activites during lectures		5	Test paper	50
Practical lessons		15	Oral examination
Projects
Colloquia		30
Seminars