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ZP282 - Organic chemistry II

Course specification
Course titleOrganic chemistry II
AcronymZP282
Study programme
Module
Lecturer (for classes)
Lecturer/Associate (for practice)
Lecturer/Associate (for OTC)
    ESPB7.0Status
    ConditionOrganic chemistry IОблик условљености
    The goalIntroduction to the basic concepts of the structure and reactions of organic compounds, the nomenclature of organic compounds, dependence of the physical and chemical properties and molecular structure, the possibilities of synthesis of organic molecules and their application. Correlation between the structure and reactivity of organic molecules and its application.
    The outcomeStudents will acquire basic theoretical knowledge of organic chemistry and together with the gained laboratory skills it will allow them to solve problems of the synthesis and reactivity of organic molecules.
    Contents
    Contents of lecturesAmines and their derivatives: synthesis and properties. Correlation between the structure and basicity of amines. Diazotization and diazo coupling reactions. Application in the synthesis. Nitro compounds: structure and properties. Aromatic nitro compounds, explosives. Aldehydes and ketones: structure, properties and synthesis. Nucleophilic addition to carbonyl group. Enolates and enols. Keto-enol equilibrium. Aldol reaction. Properties of α, β-unsaturated aldehydes and ketones and the conjugate addition reactions. Carboxylic acids: structure, properties and synthesis. Correlation between the structure and acidity. Reactions of carboxylic acids. Conversion to derivatives. Nucleophilic acyl substitution. α-Halogen substituted acids and their reactions. Carboxylic acids derivatives: acyl-halides, anhydrides, esters, amides and nitriles. The structure, properties, synthesis and reactivity in nucleophilic acyl substitution reaction. Synthesis and reactions of β-dikarbonilnih compounds. Ester enolates and Claisen condensation. Malonic ester and acetoacetic ester synthesis. Strategy of synthesis. Carbohydrates: polyfunctional natural compounds. Lipids. Heterocyclic aromatic compounds: structure and properties. Five- and six-member rings. Synthesis and characteristic reactions. Condensed ring systems. Amino acids, proteins and nucleic acids.
    Contents of exercisesSynthesis of 6 organic compounds that illustrate the most important organic reactions.
    Literature
    1. K.P.C. Volhard, N.E. Šor, Organska hemija: struktura i funkcija, 4. izdanje, Data Status: Nauka, Beograd: Planeta print, 2004. (Original title)
    2. N.E. Šor, Uputstvo za rešavanje zadataka sa rešenjima. Organska hemija: struktura i funkcija, 4. izdanje, Data Status: Nauka, Beograd: SP Print, 2006. (Original title)
    3. Grupa autora, Eksperimentalna organska hemija, 4. izdanje, TMF, Beograd, 2011. (Original title)
    4. Grupa autora, Zbirka zadataka iz organske hemije, TMF, Beograd, 2000. (Original title)
    5. T.W. Graham Solomons, C.B. Fryhle, Organic Chemistry, 9th ed., John Wiley Inc, New York, 2007. (Original title)
    Number of hours per week during the semester/trimester/year
    LecturesExercisesOTCStudy and ResearchOther classes
    402
    Methods of teachingLectures, Organic Chemistry Laboratory, Written mid-term exams.
    Knowledge score (maximum points 100)
    Pre obligationsPointsFinal examPoints
    Activites during lectures5Test paper50
    Practical lessons15Oral examination
    Projects
    Colloquia30
    Seminars