14HFI38 - Pharmaceutical Engineering Basics

Course specification
Course titlePharmaceutical Engineering Basics
Study programmeChemical Engineering
Lecturer (for classes)
Lecturer/Associate (for practice)
Lecturer/Associate (for OTC)
    ConditionОблик условљености
    The goal1. Introduction to the conventional and modern pharmaceutical forms of preparation. ; 2. Introduction to the basic principles of drug distribution and dissolution on the macro levels in the body. ; 3. Introduction to the work in the sterile environment and basic principles for pharmaceutical products production and packaging in the view of pharmaceutical regulatory, validation, quality controle and good manufacturing practice. ; 4. Introduction to the basic specificities of the pharmaceutical processes. ; 5. Inhabitation of students with the team work for further development and specialization of the interdisciplinary aproach to the practical problem solving. ;
    The outcome1. Students are enabled for work in sterile conditions. ; 2. Students are initiate with the basic specificities of the pharmaceutical processes. ; 3. Students are enabled for production of the microbeads (alginate matrix particles produced by different atomization techniques), liposome type vesiqules and phospholipide emulsions and water for injection (WFI). ; 4. Students attain basic knowledge for modern separation proceses in pharmaceutical engineering. ; 5. Students attain basic knowledge for the work in the industry trough the visits to the pharmaceutical companies. ;
    Contents of lecturesCourse include studing of conventional and modern forms of pharmaceutical products with ; special attention for the principles and design of transfer of the active component to the ; targeted place in organism. ;
    Contents of exercisesPractical part include laboratory practice for basic incapsulation techniques, laboratory work ; in sterile conditions (work in laminar, work with autoclave), methods for preparation and ; characterization of pharmaceutical products (microscopy). Calculation and selection of some ; separation processes, example of the production of water for injection (WFI). ;
    1. Bioprocesno inženjerstvo, M. Milivojević, V. Đorđević, B. Bugarski, V. Nedović, Akademska Misao 2013. (Original title)
    2. I. Jalšenjak, V. Jalšenjak, J. Filipović-Grčić, Farmaceutika, Školska knjiga d.d., Zagreb, (1998). (Original title)
    3. G. A. Lewis, D. Mathieu and R. P. Than Luu, Pharmaceutical Experimental Design , Marcel Dekker, 1999 (Original title)
    4. Gilbert S. Nanker, C. T. Rhodes, Modern Pharmaceuticals , Marcel Dekker, 2002. (Original title)
    5. Materijal sa predavanja. (Original title)
    6. N.V. Majeti, R.Kumar, N.Kumar, A.J. Domb, M.Arora, Pharmaceutical Polymeric Controlled Drug Delivery Systems, Advances in Polymer Science, 160, 45-117. (Original title)
    7. I.A.K. Amashta, O.K. Trabanca, D.K. Trabanca, Los materiales inteligentes de este milenio: Los hidrogeles macromoleulares , sintesis, propiedades y aplicacciones, Universidad del Pais Vasco, (2003), ISBN: 84-8373-637-3. (Original title)
    8. N.V. Majeti, R. Kumar, Nano and Microparticles as Controlled Drug Delivery Devices, J. Pharm. Pharmaceut. Sci., 3 (2), (2000) 234-258. (Original title)
    9. C. Valenta, B.G. Auner, The Use of Polymers for Dermal and Transdermal Delivery, European Journal of Pharmaceutics and Biopharmaceutics, 58, (2004) 279-289. (Original title)
    10. R. Hejazi, M. Amiji, Chitosan-based gastrointestinal delivery systems, Journal of Controlled Release, 89, (2003) 151-165. S.A. Agnihorti, N.N. Mallikurjuna, T.M. Aminabhavi, Racent advances on chitosan-based micro- and nanoparticles in drug delivery, Journal of Controlled Release, 100, (2004) 5-28. M.R. ten Breteler, V.A:Nierstrasz, M.M.C.G.Warmoeskerken, Textile Slow-release systems with medical appications, Autex Research Journal, 2(4) (2002), 176-189. (Original title)
    Number of hours per week during the semester/trimester/year
    LecturesExercisesOTCStudy and ResearchOther classes
    Methods of teaching
    Knowledge score (maximum points 100)
    Pre obligationsPointsFinal examPoints
    Activites during lecturesTest paper
    Practical lessons20Oral examination50