14D160 - Polymeric biomaterials

Course specification
Course titlePolymeric biomaterials
Study programme
Lecturer (for classes)
Lecturer/Associate (for practice)
    Lecturer/Associate (for OTC)
      ConditionNoОблик условљености
      The goalIntroduction in polymeric biomaterials, methods of their synthesis and characterization, and the most important applications in medicine, pharmacy and dentistry.
      The outcomeStudents acquire knowledge in the methods of polymer synthesis, their structure, properties and possibilities of application of polymeric biomaterials as drug delivery systems, for tissue and organ reconstruction and regeneration and in the design of various medical devices for use in medicine, pharmacy and dentistry. Based on these skills they are capable to select optimal polymeric biomaterial and method of material synthesis for the desired application.
      Contents of lecturesPolymeric Biomaterials: structure, properties, characterization, classification and application of polymeric biomaterials. Classification of medical devices. Methods for testing polymeric biomaterials. Important natural and synthetic polymeric biomaterials. Biodegradability and biodegradation mechanisms-polylactides and polyglycolides. Stimuli-sensitive polymeric biomaterials -"intelligent hydrogels". Hydrogels-structural and kinetic parameters, mechanical and diffusion properties. Hydrogels based on poly (2-hydroxyethyl (meth)acrylate), chitosan and alginate. Hydrogels loaded with therapeutically active metal ions in controlled drug release systems. Polymeric nanoparticles for controlled release. Medical devices based on polymeric biomaterials for dermal and transdermal drug release. Bioadhesion and mucoadhesion. Bioadhesives in dermatology, surgery and dentistry. Polymeric biomaterials in tissue regeneration. Antimicrobial polymeric biomaterials. Biofunctionality-biocompatibility and biological response during application. Sterilization of medical devices. Medical devices design and regulation.
      Contents of exercises
      1. S. Tomić, J. Filipović, Polimerni biomaterijali, Internal material, OHT Department, Faculty of Technology and Metallurgy, Belgrade, 2013.
      2. S. Dimitriu, Polymeric biomaterials, Marcel Dekker, 2013.
      3. J.B. Park, R.S. Lakes, Biomaterials-An Introduction, Springer, 2007.
      Number of hours per week during the semester/trimester/year
      LecturesExercisesOTCStudy and ResearchOther classes
      Methods of teachingLessons and consultations
      Knowledge score (maximum points 100)
      Pre obligationsPointsFinal examPoints
      Activites during lecturesTest paper50
      Practical lessonsOral examination