D192 - Physico-chemical basis of pharmaceutical engineering

Course specification
Course titlePhysico-chemical basis of pharmaceutical engineering
Study programme
Lecturer (for classes)
Lecturer/Associate (for practice)
Lecturer/Associate (for OTC)
    ConditionОблик условљености
    The goalThe aim of this course is to introduce students to the modern methodology of the drugs production in pharmaceutical industry. ;
    The outcomeIn this course, students acquire knowledge and practice for a) aseptic operation, b) techniques of immobilization-encapsulation c) writting the experimental protocols. Students gain the knowledge necessary to research and develope processes in pharmaceutica engineering and apply engineering principles to their analysis. Upon successful completion of the course, students acquire: (i) the ability to research and apply modern techniques for encapsulation of active substances (ii) of the basic knowledge and skills required for sterile operation (iii) knowledge of the specific needs, requirements and regulations (GLP, GMP) necessary in the pharmaceutical practice.
    Contents of lecturesThe course introduces students to the basic principles of the pharmaceutical engineering process. Teaching Units: Principles of drugs adsorption, Drugs formulations and methods of administration, Pharmacokinetics, Methods of drug use and distribution, Mechanisms of the controlled release, Video Image Systems for particle characterization, Current regulations in the pharmaceutical manufacturing and tehnoekonomical verification of enzyme. Students independently work out seminar and are trained for independent laboratory work under sterile conditions. The course includes an experimental work of the students with the techniques of immobilization and encapsulation of active substances.
    Contents of exercises;
    1. Bioprocesno Inzenjerstvo, M. Milivojevic, B. Bugarski, V. Djordjevic, V Nedovic, Akademska misao, Beograd, 2013. ; ; ;
    2. Bugarski, B., Projektovanje uređaja i procesa u biotehnologiji i biohemijskom inženjerstvu, Akademska misao, Beograd, 2006. ; ;
    3. Gilbert S Banker., Modern Pharmaceuticals Marsel Dekker., 2002 ; ; ; ;
    4. Lewis G, Pharmaceutical Experimental Design., Marsel Dekker , 1999 ; ;
    5. Sidney H, GMP, for pharmaceuticals, Marsel Dekker , 20004. Pharmakokinetics, Gibaldi M, Marsel Dekker , 2001 ; ; ;
    Number of hours per week during the semester/trimester/year
    LecturesExercisesOTCStudy and ResearchOther classes
    Methods of teachingLectures, problem solving, consultation, lab work.
    Knowledge score (maximum points 100)
    Pre obligationsPointsFinal examPoints
    Activites during lecturesTest paper
    Practical lessonsOral examination50