D106BB - Cell Engineering

Course specification
Course titleCell Engineering
Study programme
Lecturer (for classes)
Lecturer/Associate (for practice)
    Lecturer/Associate (for OTC)
      ConditionОблик условљености
      The goalThe aim of the subject is that students aquire knowledge about the major principles and methods of cell cullturing, conditions and treatments which should be undertaken in order to an achieve optimal metabolic and genetic requirements for the specific needs in biotechnology.
      The outcomeAcquiring of the principles and techniques of cell engineering for various biotechnological processes. By acquiring these principles, calculations and techniques the students will be able to select the most appropriate production microorganism, make a strategy and apply techiques for the improvement of microbial productivity and characteristics for specific needs.
      Contents of lecturesThe course encompasses the methods and principles of cell cullturing, Designing and requirements for the production microorganism. Techniques and methods for the improvement of the productivity of cells. Cell immobilization (bacteria, animal and plant cells) for various applications in biotechnology. The bioreactor types appropriate for various cells. Kinetic of celll growth. Various working regimes of bioreactors. Mass and energy balans in bioreactors.
      Contents of exercisesThe course is based on lectures which also include calculations an also LAB practice and research study. ; Calculation examples include kinetic of microbial growth and production for various purposes, in different types of reactors, under different conditions, and working regimes. ;
      1. Ljiljana Mojović, Biohemijsko inženjerstvo, TMF, Beograd, 2006.
      2. Michael L. Shuler, Fikret Kargi, Bioprocess engineering, Basic concepts, sec. edition. 2002, PHI, India
      3. M. Rakin, L. Mojović, “Biohemijsko inženjerstvo“, Zbirka rešenih zadataka sa teorijskim osnovama, pomćni udžbenik, ISBN 978-86-7401-261-1, TMF Beograd (2009
      Number of hours per week during the semester/trimester/year
      LecturesExercisesOTCStudy and ResearchOther classes
      Methods of teachingInteractive lessons with using video presentations; biochemical and kinetic models and calculations; laboratory practice, seminars - case research studies.
      Knowledge score (maximum points 100)
      Pre obligationsPointsFinal examPoints
      Activites during lectures5Test paper50
      Practical lessons5Oral examination