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22ZP281 - Organic chemistry I

Course specification
Course titleOrganic chemistry I
Acronym22ZP281
Study programmeBiochemical Engineering and Biotechnology
Module
Lecturer (for classes)
Lecturer/Associate (for practice)
    Lecturer/Associate (for OTC)
      ESPB6.0Status
      ConditionGeneral Chemistry 1Облик условљености
      The goalIntroduction to the basic concepts of the structure and reactions of organic compounds, the nomenclature of organic compounds, dependence of the physical and chemical properties and molecular structure, the possibilities of synthesis of organic molecules and their application.
      The outcomeStudents will acquire basic theoretical knowledge of organic chemistry and together with the gained practical knowledge of techniques and operations in organic chemistry laboratory it will allow them to solve the problems of the synthesis and reactivity of organic molecules.
      Contents
      Contents of lecturesOrganic compounds and chemical bonds. A classification of organic compounds: functional groups. Alkanes and cycloalkanes: properties and conformation analysis. Radical halogenation (chain mechanism) and reactivity. Stereochemistry: constitutional isomers and stereoisomers. Chiral molecules (R,S–system). Optical activity. Haloalkanes: properties and synthesis. Bimolecular and monomolecular nucleophilic substitution (SN1 and SN2 reaction). Elimination reactions (E1 and E2). Stereochemistry of reactions. Alkenes and alkynes: properties and synthesis. Electrophilic and radical addition. Dimerization, oligomerization and polymerization of alkenes. Reactivity of alkenyl halides. Conjugated dienes. Electrophilic addition to conjugated dienes. Polymerization of conjugated dienes. Aromatic compounds: benzene and aromaticity. Huckel's rule of aromaticity. Synthesis of benzene derivatives: electrophilic aromatic substitution. Reactivity and regioselectivity. Organometallic compounds: synthesis, properties and application in the synthesis. Alcohols and ethers: properties and synthesis. Sulfur analogues of alcohols and ethers. Phenols and aryl halides. Nucleophilic aromatic substitution. Chemical properties of phenol.
      Contents of exercisesExperimental techniques in organic chemistry laboratory. Basic methods of separation and purification of organic substances. Synthesis of 2-3 organic compounds.
      Literature
      1. K.P.C. Vollhardt, N.E. Schore, Organic Chemistry: Structure and Function, 6th ed., W. H. Freeman, New York, 2010.
      2. Group of authors, Experimental Organic Chemistry, 7th ed., TMF, Belgrade, 2019. in Serbian
      3. Group of authors, A Collection of Problems in Organic Chemistry, TMF, Belgrade, 2000. in Serbian
      4. T.W. Graham Solomons, C.B. Fryhle, Organic Chemistry, 9th ed., John Wiley Inc, New York, 2007.
      5. T.W. Graham Solomons, C.B. Fryhle, R.G. Johnson, Study Guide and Solutions Manual for Organic Chemistry, 9th ed., John Wiley Inc, New York, 2007.
      Number of hours per week during the semester/trimester/year
      LecturesExercisesOTCStudy and ResearchOther classes
      42
      Methods of teachingLectures, Organic Chemistry Laboratory, Written mid-term exams.
      Knowledge score (maximum points 100)
      Pre obligationsPointsFinal examPoints
      Activites during lectures5Test paper50
      Practical lessons15Oral examination
      Projects
      Colloquia30
      Seminars