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22MPIBS - Design and Selection of Bioreactor System

Course specification
Course titleDesign and Selection of Bioreactor System
Acronym22MPIBS
Study programme
Module
Lecturer (for classes)
Lecturer/Associate (for practice)
Lecturer/Associate (for OTC)
    ESPB4.0Status
    ConditionОблик условљености
    The goalObjective of the course is to initiate students with use and selection of various types of bioreactors for the basic bioprocesses (enzimatic and microbic, inhibited and autocatalised; aerobic and anaerobic). Students learn how to determine kinetics of process based on experimental data and how to determine volumes and retention times for the basic types of reactors. Students are initiated with the modern types of bioreactors and their use including the selection of the optimal reactor type and arrangement for different processes.
    The outcomeStudents are enabled to determine kinetics of enzyme and micrоbial processes based on the experimental data. Students learn how to chose the best type of bioreactor and how to calculate its working volume for the basic bioprocesses enzimatic and microbic, inhibited and autocatalised, aerobic and anaerobic. Students learn how to choose the best configuration of several reactors and gain knowledge about modern trends in this area.
    Contents
    Contents of lecturesKinetics and stehiometry of bioprocesses and the influence of different parameters on them (pH, temperature, products, immobilization...). Determination of Batch, Plugflow, and Stired; Tank reactors dimensions for enzyme and microbial fermentations. Bioreactors for aerobic processes. Determining of the optimal working conditions of the bioreactor and optimal organization of multiple bioreactors in bioprocesses. Selection and design of the bioreactor in order to attain required conditions for bioprocess. Modern types of bioreactors and their use.
    Contents of exercisesDeterminition of the stechiometric and kinetic parameters for enzyme and microbial reactions (uninhibited and inhibited). Calculation and compatition of basic types of bioreactors. Design and calculation of aerobic bioreactor. Calclulation of the system of bioreactors.
    Literature
    1. Биопроцесно инжењерство, М. Миливојевић, В. Ђорђевић, Б. Бугарски, В. Недовић, Академска Мисао 2013.
    2. Пројектовање процеса у биотехнологији и биохемиском инжењерству , Б.Бугарски, Академска мисао, 2006.
    3. Octave Levenspiel, Chemical Reactor Omnibook, Oregon St Univ Bookstores, 1993.
    4. Octave Levenspiel, Chemical Reaction Engineering (in Serbian), TMF, Belgrade, 1979.
    Number of hours per week during the semester/trimester/year
    LecturesExercisesOTCStudy and ResearchOther classes
    22
    Methods of teachingLectures, problem solving, consultation.
    Knowledge score (maximum points 100)
    Pre obligationsPointsFinal examPoints
    Activites during lectures10Test paper30
    Practical lessonsOral examination
    Projects
    Colloquia40
    Seminars20