22DBKP - Biochemical kinetics
| Course specification | ||||
|---|---|---|---|---|
| Course title | Biochemical kinetics | |||
| Acronym | 22DBKP | |||
| Study programme | Biochemical Engineering and Biotechnology,Chemistry,Material Engineering | |||
| Module | ||||
| Lecturer (for classes) | ||||
| Lecturer/Associate (for practice) | ||||
| Lecturer/Associate (for OTC) | ||||
| ESPB | 6.0 | Status | ||
| Condition | none | Облик условљености | ||
| The goal | The aim of the course is to teach the students specialized and novel trends and achievements in the area of biochemical kinetics as well as provide experience in modern tools and techniques of kinetic analysis based on selected examples from the scientific literature by using software packages specialized for biochemical reactions. The aim is also to provide the students competences to critically analyze the relevance of the kinetic models, and gain knowledge how they can be used in a practical fashion to design and optimize biochemical processes. | |||
| The outcome | (i) Students gained skills and knowledge to critically analyze kinetic data as well as to independently adapt optimal kinetic models for describing complex biochemical reactions in different systems; (ii) Students gained technical competencies to use software packages specialized for biochemical reactions (Matematica, EZ-FIT V1.1, ENCORA 1.2; DynaFit); (iii) Students gained competencies to use specialized knowledge for critical analysis and evaluation of the adequacy of the corresponding models in specific cases and on that basis to make strategic decisions; (iv) Students gained communication and social competencies required for work in a team of engineers. | |||
| Contents | ||||
| Contents of lectures | This course will explore the theoretical and practical aspects of both enzyme and microbial kinetics. Topics covered include: 1) determination of steady state rate equations: the analysis of progresss curves and results; 2) kinetics of reversible and multisubstrate enzyme reactions, 3) pH and temperature dependence of enzyme-catalyzed complex reactions, 4) sigmoidal kinetics and allosteric enzymes (sequential interaction model and symmetry model), 5) enzyme kinetics with immobilized enzymes in heterogeneous system; 6) kinetics of protein and enzyme denaturation. Topics from microbial process include kinetic description of microbial growth in complex systems; nonisothermal growth modeling; mixed substrate utilization and microbial competition and kinetics of multiple-nutrient-controlled growth. | |||
| Contents of exercises | ||||
| Literature | ||||
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| Number of hours per week during the semester/trimester/year | ||||
| Lectures | Exercises | OTC | Study and Research | Other classes |
| 3 | ||||
| Methods of teaching | The course consists of lectures, exercises, computer simulations. | |||
| Knowledge score (maximum points 100) | ||||
| Pre obligations | Points | Final exam | Points | |
| Activites during lectures | Test paper | 50 | ||
| Practical lessons | 20 | Oral examination | ||
| Projects | ||||
| Colloquia | ||||
| Seminars | 15 | |||