14MHFI9 - Unit operations in pharmaceutical engineering

Course specification
Course title		Unit operations in pharmaceutical engineering
Acronym		14MHFI9
Study programme		Chemical engineering
Module
Lecturer (for classes)		prof. dr Rada Pjanović
Lecturer/Associate (for practice)		prof. dr Rada Pjanović
Lecturer/Associate (for OTC)
ESPB		3.0	Status
Condition		Mechanical operations, Heat transfer operations, Mass transfer operations	Облик условљености
The goal		The goal of course is that student learns more about unit operations widely used in pharmaceutical industry, learns basic principles and calculations of these operations and realize how to use literature.
The outcome		Student will be capable to select and use appropriate unit operations in the process in the pharmaceutical industry. Student learns to establish momentum, heat and mass balances for the basic unit operations and to do basic equipment design.
Contents
Contents of lectures		Specific unit operations in pharmaceutical industry. Working under the clean and sterile conditions. Particles characterization. Grinding and sieving of particles. Powders mixing. Mixing and homogenization of liquids. Mixing in the fluidized beds. Filtration and sedimentation. Membrane filtration and ultrafiltration. Heat transfer in the mixing vessels. Vacuum evaporation. Liquid–liquid extraction. Solid–liquid extraction. Crystallization. Chromatography – preparative. Drying and lyophilization. Immobilization, encapsulation and controlled release.
Contents of exercises		Problem solving. Lab exercise.
Literature
Jalešnjak I., Jalešnjak V., Filipović-Grčić J., Pharmaceutics (in serbian), Školska knjiga, Zagreb, 1998. Cvijović S., Bošković-Vragolović N., Pjanović R., Mass transfer operations – problems with theory basics (in serbian), Akademska misao, Beograd, 2007. Duduković A., Mass transfer operations (in serbian), Akademska misao, Beograd, 2008. Grbavčić Ž., Multiphase systems (in serbian)
Number of hours per week during the semester/trimester/year
Lectures	Exercises	OTC	Study and Research	Other classes
2	1
Methods of teaching		Lectures, problem solving, lab exercise, consultation.
Knowledge score (maximum points 100)
Pre obligations		Points	Final exam	Points
Activites during lectures			Test paper	30
Practical lessons			Oral examination
Projects
Colloquia		70
Seminars