14D020 - Scale-Up

Course specification
Course titleScale-Up
Study programme
Lecturer (for classes)
Lecturer/Associate (for practice)
Lecturer/Associate (for OTC)
    ConditionОблик условљености
    The goalThe goal of the course is to introduce to the students the methodology of scale-up of the processes, and to developed the ability to properly define the design parameters of the industrial systems, based on mathematical model calculations, laboratory and pilot-plant research.
    The outcomeThe ability to apply basic principles of scale-up of the process in process equipment sizing based on mathematical model calculations and laboratory and pilot plant tests.
    Contents of lecturesIntroduction. Scale-up of the process as complex and specific part of chemical engineering; numerous factors that influence the scale-up of the small (laboratory) systems to industrial ones; empirical, mathematical and other methods of extrapolation. The significance and limitations of empirical correlations. Similarity theory, geometric, mechanical, thermal and chemical similarity criteria and proofs; simulations of the processes with and without chemical reaction; Process modeling - general, marginal conditions, modeling of the phenomena. System modeling - theory and methods. Scale-up modeling; scaling exponents, the complexity of the systems with simultaneous active transport phenomena and chemical reactions, the conditions and criteria of similarity that apply to these systems. Reactions in homogeneous and heterogeneous systems. Single-phase systems and reactors – scale-up. Analogy of the phenomena - mathematical isomorphism, various analogies in physico-chemical, physical and chemical processes. Hydrodynamic analogy-theory and application. Pilot plant and pilot plant facilities, the importance of experiments. Typical examples: Mixing, multiphase systems, heat transfer, chemical reactors.
    Contents of exercisesCalculation exercises.
    1. Materials from the lectures, presentations
    2. M. Zlokarnik, Scale-up in Chemical Engineering, Wiley-VCH Verlag GmbH&Co.KgaA, New York, 2002.
    3. R.E. Johnstone, Pilot Plants, Models and Scale-up methods in Chemical Engineering, McGraw-Hill, New York, 1957.
    4. Bachurst, J.R., Harker, J.H., “Process Plant Design”, Heinemann, London, 1973.
    5. Seider, D.W., “Proces design principles: synthesis, analysis and evaluation”, Wiley Inc., New York, 1999.
    Number of hours per week during the semester/trimester/year
    LecturesExercisesOTCStudy and ResearchOther classes
    Methods of teachingLectures, calculation exercises, consultations
    Knowledge score (maximum points 100)
    Pre obligationsPointsFinal examPoints
    Activites during lecturesTest paper
    Practical lessonsOral examination