MKO - Controlled release

Course specification
Course titleControlled release
Study programme
Lecturer (for classes)
Lecturer/Associate (for practice)
Lecturer/Associate (for OTC)
    ConditionОблик условљености
    The goalThe objective is that student learns about: systems for controlled release, mass transfer in different systems and use of controlled release in different industries e.g. pharmaceutical, food, cosmetics. Student should learn about different ways of production of carriers for actives compounds.
    The outcomeStudent acquires basic knowledge about systems for controlled release. Student learns about advantages and weaknesses of new controlled delivery systems comparing to each other and to conventional systems.
    Contents of lecturesPrinciples of controlled release. Molecular diffusion – steady and non-steady. Encapsulation of actives in the reservoir type of particles and mass transfer from these particles. Encapsulation of actives in the matrix particles and mass transfer from these particles. Diffusion in polymer systems and use of polymers for controlled release. Micro and nanoparticles as novel systems for controlled release. Emulsions and microemulsions. Mechanism of actives release. Use of controlled release in pharmacy, food industry, cosmetics and pesticide production.
    Contents of exercisesProblem solving. Lab exercise.
    1. Handout from lectures.
    2. Jalešnjak I., Jalešnjak V., Filipović-Grčić J., Pharmaceutics (in serbian), Školska knjiga, Zagreb, 1998.
    3. Adrian Williams, Transdermal and Topical Drug Delivery, Pharmaceutical Press, 2003.
    4. Mikael Hedenqvist, Transport Properties of Polymers, Royal Institute of Technology, Stockholm, 2002.
    5. Meyer Rosen, Delivery System Handbook for Personal Care and Cosmetic – Technology, Applications and Formulations, William Andrew Inc, 2005.
    6. James Swarbrick, Encyclopedia of Pharmaceutical Technology, Third Edition, Informa Healthcare USA, Inc., 2007.
    Number of hours per week during the semester/trimester/year
    LecturesExercisesOTCStudy and ResearchOther classes
    Methods of teachingLectures, problem solving, lab exercise, consultation.
    Knowledge score (maximum points 100)
    Pre obligationsPointsFinal examPoints
    Activites during lecturesTest paper30
    Practical lessonsOral examination