MKO - Controlled release

Course specification
Course title		Controlled release
Acronym		MKO
Study programme		Chemical engineering,Material Engineering
Module
Lecturer (for classes)		prof. dr Rada Pjanović
Lecturer/Associate (for practice)		prof. dr Rada Pjanović
Lecturer/Associate (for OTC)
ESPB		4.0	Status
Condition			Облик условљености
The goal		The objective is that student learns about: systems for controlled release, mass transfer in different systems and use of controlled release in different industries e.g. pharmaceutical, food, cosmetics. Student should learn about different ways of production of carriers for actives compounds.
The outcome		Student acquires basic knowledge about systems for controlled release. Student learns about advantages and weaknesses of new controlled delivery systems comparing to each other and to conventional systems.
Contents
Contents of lectures		Principles of controlled release. Molecular diffusion – steady and non-steady. Encapsulation of actives in the reservoir type of particles and mass transfer from these particles. Encapsulation of actives in the matrix particles and mass transfer from these particles. Diffusion in polymer systems and use of polymers for controlled release. Micro and nanoparticles as novel systems for controlled release. Emulsions and microemulsions. Mechanism of actives release. Use of controlled release in pharmacy, food industry, cosmetics and pesticide production.
Contents of exercises		Problem solving. Lab exercise.
Literature
Handout from lectures. Jalešnjak I., Jalešnjak V., Filipović-Grčić J., Pharmaceutics (in serbian), Školska knjiga, Zagreb, 1998. Adrian Williams, Transdermal and Topical Drug Delivery, Pharmaceutical Press, 2003. Mikael Hedenqvist, Transport Properties of Polymers, Royal Institute of Technology, Stockholm, 2002. Meyer Rosen, Delivery System Handbook for Personal Care and Cosmetic – Technology, Applications and Formulations, William Andrew Inc, 2005. James Swarbrick, Encyclopedia of Pharmaceutical Technology, Third Edition, Informa Healthcare USA, Inc., 2007.
Number of hours per week during the semester/trimester/year
Lectures	Exercises	OTC	Study and Research	Other classes
2	1	1
Methods of teaching		Lectures, problem solving, lab exercise, consultation.
Knowledge score (maximum points 100)
Pre obligations		Points	Final exam	Points
Activites during lectures			Test paper	30
Practical lessons			Oral examination
Projects
Colloquia		20
Seminars		50