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D180 - The Chemistry of the Physiologically Active Compounds

Course specification
Course titleThe Chemistry of the Physiologically Active Compounds
AcronymD180
Study programme
Module
Lecturer (for classes)
Lecturer/Associate (for practice)
    Lecturer/Associate (for OTC)
      ESPB5.0Status
      ConditionОблик условљености
      The goalThe aim of the course is to get students acquainted with the basic principles of the action of the physiologically active compounds. The special accent is on the link between the chemical structure and the action mechanism. The overview of the kinds of receptor and the receptor-medicine interaction is given, as well as the detailed overview of the different pharmacokinetical agents.
      The outcomeThe students will acquire the necessary expert knowledge for critical analysis and combining of new complex ideas, as well as the capability to develop new ideas. They will analyze, value and align new ideas and be able to make strategic decisions. ;
      Contents
      Contents of lecturesThe basic concept of pharmamaceutical medicinal chemistry: stereochemistry of drugs, physico-chemical ad biopharmaceutical properties, phamacokinetics, metabolism of drugs, the mechanism of drugs actions. The overview of different pharmacodynamic agents: drugs affecting the central nervous system; cardiovascular system, hormonal and immune system, chemotherapeutic agents.
      Contents of exercises
      Literature
      1. Burger's Medicinal Chemistry and Drug Discovery¨, vol.I-V, sixth edition, ed. Abraham, J.D., John Wiley & Sons, New Jersey, 2003.
      2. Ison and Gisvold's "Textbook of Organic Medicinal and Pharmaceutical Chemistry" , J.B. Lippincott Company, London, 1998.
      3. Foye's Principles of Medicinal Chemistry 6th Edition, Wolkers, Kuver & Lippincott, Williams & Wilkins, Philadelphia, 2008.
      4. D.Radulović, S.Vladimirov, Farmaceutska hemija, I deo, Grafopan, Beograd, 2005.
      5. H.P.Rang, M.M.Dale, J.M.Ritter, P.K.Moore, 5.Pharmacology, 5th Edition, Data Status, Beograd, 2005.
      Number of hours per week during the semester/trimester/year
      LecturesExercisesOTCStudy and ResearchOther classes
      2
      Methods of teachingLectures
      Knowledge score (maximum points 100)
      Pre obligationsPointsFinal examPoints
      Activites during lecturesTest paper
      Practical lessonsOral examination50
      Projects
      Colloquia
      Seminars50