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14HFI412 - Pharmaceutical Biotechnology

Course specification
Course titlePharmaceutical Biotechnology
Acronym14HFI412
Study programmeChemical Engineering
Module
Lecturer (for classes)
Lecturer/Associate (for practice)
Lecturer/Associate (for OTC)
    ESPB4.0Status
    ConditionAttended courses: Biochemistry, MicrobiologyОблик условљености
    The goalThe aim of the course is that students acquire knowledge of basic biotechnological processes for the production of pharmaceutical products, diagnostic tools and genetic therapeutics. This knowledge will make the students competent to work in modern biopharmaceutical industry.
    The outcomeThe course prepares students to master biotechnological processes and techniques for the production of biopharmaceuticals.
    Contents
    Contents of lecturesBasic biotechnological processes for the production of pharmaceuticals based on using live cells (bacteria, animal cells, and plant cells), enzymes, tissue culture, DNA or live organisms. The main groups of biopharmaceuticals which are being studied are: antibiotics, vitamins, antibodies, vaccines, interferon and interleukins, hematopoietic factors, therapeutic hormones (insulin), anticoagulants and thrombolytic agents.The course is based on lectures which also include calculations and experimental practice.
    Contents of exercisesPractical lessons consists of lab setup of one traditional (fermentation) technology for the production of pharmaceuticals, isolation of the microorganisms for the production of antibiotics, creating an antibiogram, detection of MIC of antibiotic; methods for the analysis, of proteins, methods for the analysis of vitamins, isolation of DNA from biological material.
    Literature
    1. Ljiljana Mojović, Farmaceutska biotehnologija, udžbenik, TMF, Beograd, 2008. (Original title)
    2. Walsh G., Biopharmaceuticals: Biochemistry and Biotechnology (Hardcover). Publisher: John Wiley & Sons; 2nd edition, 2003 (Original title)
    3. Daan J. A. Crommelin, Daan J.A. Crommelin, Robert D. Sindelar Pharmaceutical Biotechnology (Hardcover), 2 nd edition, Taylor and Francis, 2002 (Original title)
    Number of hours per week during the semester/trimester/year
    LecturesExercisesOTCStudy and ResearchOther classes
    211
    Methods of teachingInteractive lessons with using video presentations; biochemical and kinetic models and calculations; laboratory practice, seminars and homeworks.
    Knowledge score (maximum points 100)
    Pre obligationsPointsFinal examPoints
    Activites during lectures5Test paper50
    Practical lessons20Oral examination
    Projects
    Colloquia10
    Seminars15