22D115 - Scale-up in Chemical Engineering

Course specification
Course title		Scale-up in Chemical Engineering
Acronym		22D115
Study programme		Biochemical Engineering and Biotechnology,Chemical Engineering
Module
Lecturer (for classes)		doc. dr Danica Brzić
Lecturer/Associate (for practice)		doc. dr Danica Brzić
Lecturer/Associate (for OTC)
ESPB		5.0	Status
Condition			Облик условљености
The goal		Methodological approach to the scale-up of processes. Learning how to use mathematical models, dimensional analysis and laboratory measurement data in order to design correctly industrial processes.
The outcome		Students are able to apply basic principles of scale-up on the design of processes and equipment based on laboratory and pilot measuremant data.
Contents
Contents of lectures		Introduction. Historical development of the scale-up. Scientific, engineering and economical aspects of scale-up. Risk factors. Theory of similarity. Geometical, mechanical, thermal and chemical similarity. Partial and total similarity. Dimensional analysis. Buckingham's pi-theorem. Empirical correlations -importance and limitations. Regime analysis of processes and characteristic times. Various case studies refering to mechanical, thermal and diffusional operations as well as reaction systems.
Contents of exercises		Calculations of scale-up problems in Chemical Engineering: Viscous flow through the pipe, Plug flow reactor with first order reaction, Power of agitation, Convective heat transfer by flowing through the pipe, Gas-liquid mass transfer in a stirred vessel.
Literature
M. Zlokarnik, Scale-up in Chemical Engineering, Wiley-VCH Verlag GmbH&Co.KgaA, New York, 2002. R.E. Johnstone, Pilot Plants, Models and Scale-up methods in Chemical Engineering, McGraw-Hill, New York, 1957. Seider, D.W., “Proces design principles: synthesis, analysis and evaluation”, Wiley Inc., New York, 1999.
Number of hours per week during the semester/trimester/year
Lectures	Exercises	OTC	Study and Research	Other classes
2	1
Methods of teaching		Lectures with presentations, students projects with consultations.
Knowledge score (maximum points 100)
Pre obligations		Points	Final exam	Points
Activites during lectures			Test paper
Practical lessons			Oral examination	30
Projects		50
Colloquia
Seminars